The Department of Health has confirmed 429 new cases of Covid-19.
Four people have died from the virus; there has now been 2,000 Covid-19 related deaths since the virus broke out in March.
Of the cases notified today, 194 cases are men while 234 are women.
Most people - 69% - are aged under 45 years of age.
The median age is 34.
Most cases, 173, are in Dublin.
Elsewhere, there are 44 new cases in Cork, 26 in Donegal, 22 in Lough and 21 in Kildare.
The remaining 143 cases are spread across 20 counties.
Meanwhile, there have been 15 additional hospitalisations in the past twenty-four hours.
In total, 290 Covid patients are being treated in hospital, 33 of whom are in intensive care.
The 14 Day incidence rate is estimated to be 116.5 per 100,00 population.
CMO Says Two Weeks Of Lockdown Could Drive Down Cases
Meanwhile, Chief Medical Officer Dr Tony Holohan said the public have the opportunity to reduce the case numbers.
"We now have two weeks to get back on track. Drive down the disease by limiting the number of daily contacts you have"
Dr Holohan asked the public to work from home and reduce close contacts "to get a reproduction rate below 0.5 by December 1st".
His Deputy, Dr Ronan Glynn said the rising number of Covid-related death is evident across the continent.
"Last week alone, Europe registered over 29,000 deaths. That is one person dying every 17 seconds," he said.